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Victor Guzov

Monsanto Company, USA

Title: Evolution of Bt proteins overcomes Bt resistance in insects

Biography

Biography: Victor Guzov

Abstract

The development of insect resistance to insecticidal proteins, such as Bt proteins, is a continuous threat to insect control traits in biotech agricultural crops. This requires constant search for insecticidal proteins with new modes of action (MOA), which enhance insect resistance management options via delaying new resistance development and combating already existing resistant insects. This presentation will describe the successful onboarding of phage-assisted continuous evolution (PACE) technology, and its application to Bt toxins for generating new MOAs.