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Kelley Moremen


Kelley Moremen

University of Georgia
USA

Biography

Kelley Moremen, PhD, is Distinguished Research Professor of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia. He received his PhD at Vanderbilt University and Postdoctoral training at MIT. Dr. Moremen is a leader in the structure, function, roles, and regulation of enzymes involved in mammalian glycan biosynthesis and catabolism. The presentation will discuss the development of a recombinant platform for production of all mammalian glycosyltransferases, glycosidases, and sulfotransferases (target gene list of >350 coding regions) in baculovirus, and mammalian cells to facilitate biochemical, enzymatic and structural studies on theenzymes and applications to chemoenzymatic synthesis.

Abstract

Abstract : Strategies for recombinant production of human glycosylation enzymes: Comparison of mammalian and insect cell expression systems