Protein Engineering

Recombinant Protein Expression

Protein Expression contains of the stages after DNA has been transcribed to messenger RNA (mRNA) from the process of Optimizing protein expression, Prokaryotic and Eukaryotic systems, Fusion protein therapeutics: Cell line & cell culture development& Protein microarray studies. Recombinant production of proteins is one of the most powerful techniques used in the Life Sciences. There are nearly 3000 people from 60-65 universities in USA working for Protein Expression. The Oxford Protein Production Facility-UK (OPPF-UK) is a UK core facility for protein production located in the Research Complex at Harwell. The project has recently received additional funding of £2.3M from the MRC to provide a range of highly specialized technologies incorporating robotic systems, for the high throughput expression, purification & crystallization of recombinant proteins.